Professor Andrew Lever




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Professorial Fellow

Telephone: 01223 338215

Professor Andrew M L Lever is Professor of Infectious Diseases and Honorary Consultant Physician at Addenbrooke's Hospital. His research interests concern retroviruses and rotaviruses, from fundamental studies of the structure of some of the retroviral molecular components through to the uses of retroviruses as gene vectors for gene therapy and understanding how they replicate in order to try and find new therapies. His group are interested in novel methods to elucidate structure of RNA. The figure shows the 3D structure of the packaging signal of HIV-1 (solved in collaboration with Professor David Klenerman) which is the structure that HIV uses to identify its own genetic material within the cell for packaging into the virus. It is the largest solved viral RNA structure. In College, he supervises second-year medics in Pathology. His hospital duties include clinical work as a specialist in infectious diseases. He is Co-Editor in Chief of Retrovirology and is on the Editorial board of a number of other Journals. He is a Fellow of the Learned Society of Wales.